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HomoloGene:1099. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FBL,  H.sapiens
fibrillarin
NP_001427.2
321 aa
FBL,  P.troglodytes
fibrillarin
XP_512658.2
321 aa
FBL,  M.mulatta
fibrillarin
XP_001088664.2
322 aa
FBL,  C.lupus
fibrillarin
XP_533671.3
328 aa
FBL,  B.taurus
fibrillarin
NP_001192329.1
322 aa
Fbl,  M.musculus
fibrillarin
NP_032017.2
327 aa
Fbl,  R.norvegicus
fibrillarin
NP_001020814.1
327 aa
fbl,  X.tropicalis
fibrillarin
NP_989101.1
325 aa
fbl,  D.rerio
fibrillarin
NP_998167.1
317 aa
Fib,  D.melanogaster
Fibrillarin
NP_523817.1
344 aa
AgaP_AGAP011244,  A.gambiae
AgaP_AGAP011244
XP_309401.4
320 aa
fib-1,  C.elegans
fib-1
NP_506691.1
352 aa
NOP1,  S.cerevisiae
NOP1
NP_010270.1
327 aa
KLLA0C04389g,  K.lactis
KLLA0C04389g
XP_452393.1
335 aa
AGOS_AER214C,  E.gossypii
AGOS_AER214C
NP_985071.1
326 aa
fib1,  S.pombe
fib1
NP_596229.1
305 aa
MGG_09195,  M.oryzae
MGG_09195
XP_003709808.1
321 aa
NCU03702,  N.crassa
NCU03702
XP_961478.1
323 aa
FIB1,  A.thaliana
FIB1
NP_568772.3
308 aa
FIB2,  A.thaliana
FIB2
NP_567724.1
320 aa
Os02g0821800,  O.sativa
Os02g0821800
NP_001048553.1
87 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

U3 snoRNP associates with fibrillarin a component of the scleroderma clumpy nucleolar domain.
Herrera-Esparza R, et al. Arch Dermatol Res 294, 310-7 (2002).
Fibrillarin binds to a 3' cis-regulatory element in pre-mRNA of uvi15+ in fission yeast.
Jang YK, et al. Biochem Biophys Res Commun 294, 1184-90 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AdoMet_MTases (cl17173)
  S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fbl includes H.sapiens FBL and R.norvegicus Fbl.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 13 species)
Actinopterygii - bony fishes (11 transcripts, 10 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (16 transcripts, 12 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (51 transcripts, 33 species)
Liliopsida - monocots (15 transcripts, 8 species)
Bryopsida - mosses (4 transcripts, 1 species)
Coniferopsida - conifers (4 transcripts, 3 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (7 transcripts, 3 species)
Pezizomycetes - ascomycetes (2 transcripts, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (5 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Oomycetes
Pythiales - oomycetes (2 transcripts, 1 species)
Peronosporales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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