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HomoloGene:11416. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   VKORC1,  H.sapiens
vitamin K epoxide reductase complex, subunit 1
    NP_076869.1
163 aa
   VKORC1,  P.troglodytes
vitamin K epoxide reductase complex subunit 1
    NP_001238859.1
163 aa
   VKORC1,  C.lupus
vitamin K epoxide reductase complex, subunit 1
    XP_005621301.1
163 aa
   VKORC1,  B.taurus
vitamin K epoxide reductase complex, subunit 1
    NP_001003903.1
163 aa
   Vkorc1,  M.musculus
vitamin K epoxide reductase complex, subunit 1
    NP_848715.1
161 aa
   Vkorc1,  R.norvegicus
vitamin K epoxide reductase complex, subunit 1
    NP_976080.1
161 aa
   vkorc1,  D.rerio
vitamin K epoxide reductase complex, subunit 1
    XP_001336460.1
171 aa
   Vkor,  D.melanogaster
Vitamin-K epoxide reductase
    NP_001014533.1
152 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Warfarin resistance.
Vitamin K-dependent clotting factors, combined deficiency of, 2.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
VKOR (pfam07884)
  Vitamin K epoxide reductase family.
VKOR (cl01729)
  Vitamin K epoxide reductase (VKOR) family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Vkorc1 includes H.sapiens VKORC1 and R.norvegicus Vkorc1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 13 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)
Arachnida - arachnids (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

 

 

 

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