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HomoloGene:86654. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   F11,  H.sapiens
coagulation factor XI
    NP_000119.1
625 aa
   F11,  P.troglodytes
coagulation factor XI
    XP_001165847.1
625 aa
   F11,  M.mulatta
coagulation factor XI-like
    XP_001090398.2
915 aa
   F11,  C.lupus
coagulation factor XI
    NP_001128595.1
624 aa
   F11,  B.taurus
coagulation factor XI
    NP_001008665.1
625 aa
   F11,  M.musculus
coagulation factor XI
    NP_082342.1
624 aa
   F11,  R.norvegicus
coagulation factor XI
    NP_001041313.1
556 aa
   F11,  G.gallus
coagulation factor XI
    XP_420678.3
631 aa
   klkb1,  X.tropicalis
kallikrein B, plasma (Fletcher factor) 1
    XP_004911242.1
629 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Factor XI deficiency, autosomal dominant.
Factor XI deficiency, autosomal recessive.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tryp_SPc (cd00190)
  Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
RIC3 (pfam15361)
  Resistance to inhibitors of cholinesterase homologue 3.
PAN_APPLE (cl00112)
  PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus F11 includes H.sapiens F11 and R.norvegicus F11.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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