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HomoloGene:68503. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TUBB3,  H.sapiens
tubulin, beta 3 class III
    NP_006077.2
450 aa
   TUBB3,  P.troglodytes
tubulin, beta 3 class III
    XP_003315297.1
450 aa
   TUBB3,  C.lupus
tubulin, beta 3 class III
    XP_005620593.1
450 aa
   TUBB3,  B.taurus
tubulin, beta 3 class III
    NP_001070595.1
450 aa
   Tubb3,  M.musculus
tubulin, beta 3 class III
    NP_075768.1
450 aa
   Tubb3,  R.norvegicus
tubulin, beta 3 class III
    NP_640347.2
450 aa
   TUBB3,  G.gallus
tubulin, beta 3 class III
    NP_001026769.1
449 aa
   tubb3,  X.tropicalis
tubulin, beta 3 class III
    NP_989408.1
449 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fibrosis of extraocular muscles, congenital, 3A.



Publications
Articles associated with genes and sequences of this homology group.

Class III β-tubulin, a novel biomarker in the human melanocyte lineage.
Locher H, et al. Differentiation 85, 173-81 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tubulin_FtsZ (cl10017)
  Tubulin/FtsZ: Family includes tubulin alpha-, beta-, gamma-, delta-, and epsilon-tubulins as well as FtsZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tubb3 includes H.sapiens TUBB3 and R.norvegicus Tubb3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 13 species)
Actinopterygii - bony fishes (12 transcripts, 8 species)
Amphibia - amphibians (6 transcripts, 2 species)
Aves - birds (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 4 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (22 transcripts, 14 species)
Liliopsida - monocots (6 transcripts, 4 species)
Bryopsida - mosses (2 transcripts, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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