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HomoloGene:697. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NPY,  H.sapiens
neuropeptide Y
    NP_000896.1
97 aa
   NPY,  P.troglodytes
neuropeptide Y
    XP_001159094.1
97 aa
   NPY,  M.mulatta
neuropeptide Y
    NP_001027986.1
97 aa
   NPY,  C.lupus
neuropeptide Y
    XP_005628694.1
97 aa
   NPY,  B.taurus
neuropeptide Y
    NP_001014845.1
97 aa
   Npy,  M.musculus
neuropeptide Y
    NP_075945.1
97 aa
   Npy,  R.norvegicus
neuropeptide Y
    NP_036746.1
98 aa
   LOC100912228,  R.norvegicus
pro-neuropeptide Y-like
    XP_003749793.1
98 aa
   NPY,  G.gallus
neuropeptide Y
    NP_990804.1
97 aa
   npy,  X.tropicalis
neuropeptide Y
    NP_001072530.1
97 aa
   npy,  D.rerio
neuropeptide Y
    NP_571149.1
96 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Neuropeptide Y genes and suicidal behaviour among schizophrenic patients.
Wang AG, et al. Psychiatr Genet 23, 139-40 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PAH (cl00111)
  Pancreatic Hormone domain, a regulator of pancreatic and gastrointestinal functions; neuropeptide Y (NPY)b, peptide YY (PYY), and pancreatic polypetide (PP) are closely related; propeptide is enzymatically cleaved to yield the mature active peptide with amidated C-terminal ends; receptor binding and activation functions may reside in the N- and C-termini respectively; occurs in neurons, intestinal endocrine cells, and pancreas; exist as monomers and dimers



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Npy includes H.sapiens NPY and R.norvegicus Npy.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Amphibia - amphibians (4 transcripts, 2 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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