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HomoloGene:78. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CST3,  H.sapiens
cystatin C
    NP_000090.1
146 aa
   CST3,  P.troglodytes
cystatin C
    XP_001146702.2
108 aa
   CST3,  M.mulatta
cystatin C
    NP_001028096.1
146 aa
   LOC607874,  C.lupus
cystatin-C-like
    XP_003639869.1
153 aa
   CST3,  B.taurus
cystatin C
    NP_776454.1
148 aa
   Cst3,  M.musculus
cystatin C
    NP_034106.2
140 aa
   Cst3,  R.norvegicus
cystatin C
    NP_036969.1
140 aa
   CST3,  G.gallus
cystatin C
    NP_990831.2
151 aa
   LOC100485774,  X.tropicalis
cystatin-C-like
    XP_002934915.1
132 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cerebral amyloid angiopathy.



Publications
Articles associated with genes and sequences of this homology group.

Update on cystatin C: incorporation into clinical practice.
Shlipak MG, et al. Am J Kidney Dis 62, 595-603 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CY (cl09238)
  Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cst3 includes H.sapiens CST3 and R.norvegicus Cst3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Aves - birds (2 transcripts, 2 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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