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HomoloGene:55445. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   KAL1,  H.sapiens
Kallmann syndrome 1 sequence
    NP_000207.2
680 aa
   KAL1,  P.troglodytes
Kallmann syndrome 1 sequence
    XP_520920.3
681 aa
   KAL1,  M.mulatta
Kallmann syndrome 1 sequence
    XP_002806176.1
647 aa
   KAL1,  C.lupus
Kallmann syndrome 1 sequence
    XP_853595.3
716 aa
   LOC525898,  B.taurus
anosmin-1-like
    XP_005228592.1
678 aa
   KAL1,  G.gallus
Kallmann syndrome 1 sequence
    NP_990755.1
676 aa
   kal1,  X.tropicalis
Kallmann syndrome 1 sequence
    NP_001107160.1
683 aa
   kal1a,  D.rerio
Kallmann syndrome 1a sequence
    NP_571433.1
652 aa
   kal-1,  C.elegans
kal-1
    NP_493468.2
700 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Kallmann syndrome.



Publications
Articles associated with genes and sequences of this homology group.

X-linked GnRH deficiency: role of KAL-1 mutations in GnRH deficiency.
Hu Y & Bouloux PM. Mol Cell Endocrinol 346, 13-20 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
fn3 (pfam00041)
  Fibronectin type III domain.
FN3 (cl00065)
  Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
WAP (cl00156)
  whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of ...



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (11 transcripts, 9 species)
Mammalia - mammals (6 transcripts, 5 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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