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HomoloGene:1722. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   LAMB1,  H.sapiens
laminin, beta 1
    NP_002282.2
1786 aa
   LAMB1,  P.troglodytes
laminin, beta 1
    XP_001165667.2
1786 aa
   LAMB1,  M.mulatta
laminin, beta 1
    XP_001090393.2
1786 aa
   LAMB1,  C.lupus
laminin, beta 1
    XP_533089.4
1794 aa
   LAMB1,  B.taurus
laminin, beta 1
    NP_001193448.1
1786 aa
   Lamb1,  M.musculus
laminin B1
    NP_032508.2
1834 aa
   Lamb1,  R.norvegicus
laminin, beta 1
    XP_003750185.1
1834 aa
   LAMB1,  G.gallus
laminin, beta 1
    XP_415943.3
1785 aa
   lamb1,  X.tropicalis
laminin, beta 1
    XP_002933140.2
1782 aa
   lamb1a,  D.rerio
laminin, beta 1a
    NP_775382.1
1785 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

First Japanese case of Pierson syndrome with mutations in LAMB2.
Togawa H, et al. Pediatr Int 55, 229-31 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ATP-synt_B (pfam00430)
  ATP synthase B/B' CF(0).
ATP-synt_B (cl07975)
  ATP synthase B/B' CF(0).
Laminin_N (pfam00055)
  Laminin N-terminal (Domain VI).
Laminin_EGF (pfam00053)
  Laminin EGF-like (Domains III and V).
Tar (COG0840)
  Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].
SPEC (cl02488)
  Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
PspA_IM30 (pfam04012)
  PspA/IM30 family.
DUF745 (pfam05335)
  Protein of unknown function (DUF745).
Laminin_N (cl02806)
  Laminin N-terminal (Domain VI).
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
MCP_signal (cl19050)
  Methyl-accepting chemotaxis protein (MCP), signaling domain.
EGF_Lam (cl19065)
  Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lamb1 includes H.sapiens LAMB1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (23 transcripts, 14 species)
Actinopterygii - bony fishes (17 transcripts, 8 species)
Aves - birds (5 transcripts, 3 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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