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HomoloGene:595. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CHRNB2,  H.sapiens
cholinergic receptor, nicotinic, beta 2 (neuronal)
    NP_000739.1
502 aa
   CHRNB2,  P.troglodytes
cholinergic receptor, nicotinic, beta 2 (neuronal)
    XP_001152392.1
502 aa
   CHRNB2,  M.mulatta
cholinergic receptor, nicotinic, beta 2 (neuronal)
    XP_001114439.1
502 aa
   CHRNB2,  C.lupus
cholinergic receptor, nicotinic, beta 2 (neuronal)
    XP_547565.2
478 aa
   CHRNB2,  B.taurus
cholinergic receptor, nicotinic, beta 2 (neuronal)
    NP_001179403.1
501 aa
   Chrnb2,  M.musculus
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
    NP_033732.2
501 aa
   Chrnb2,  R.norvegicus
cholinergic receptor, nicotinic, beta 2 (neuronal)
    NP_062170.1
500 aa
   CHRNB2,  G.gallus
cholinergic receptor, nicotinic, beta 2 (neuronal)
    NP_990144.1
491 aa
   chrnb2,  X.tropicalis
cholinergic receptor, nicotinic, beta 2 (neuronal)
    NP_001093684.1
499 aa
   chrnb2b,  D.rerio
cholinergic receptor, nicotinic, beta 2b
    XP_005169811.1
543 aa
   LOC101882975,  D.rerio
neuronal acetylcholine receptor subunit beta-2-like
    XP_005174531.1
390 aa
   nAcRalpha-96Aa,  D.melanogaster
nicotinic Acetylcholine Receptor alpha 96Aa
    NP_524481.2
567 aa
   AgaP_AGAP002974,  A.gambiae
AgaP_AGAP002974
    XP_311918.3
557 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

D.melanogaster
Structural gene encoding a Drosophila homologue of a subunit of vertebrate nicotinic acetylcholine receptors (nAChR); inferred to be homologous to neuronal α subunits based on the cystein doublet at amino-acid residues 201 and 202.

H.sapiens
Epilepsy, nocturnal frontal lobe, 3.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Neur_chan_memb (pfam02932)
  Neurotransmitter-gated ion-channel transmembrane region.
Neur_chan_LBD (pfam02931)
  Neurotransmitter-gated ion-channel ligand binding domain.
Neur_chan_memb (pfam02932)
  Neurotransmitter-gated ion-channel transmembrane region.
Neur_chan_LBD (pfam02931)
  Neurotransmitter-gated ion-channel ligand binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Chrnb2 includes H.sapiens CHRNB2 and R.norvegicus Chrnb2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 7 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

 

 

 

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