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HomoloGene:2416. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TDGF1,  H.sapiens
teratocarcinoma-derived growth factor 1
    NP_003203.1
188 aa
   TDGF1,  P.troglodytes
teratocarcinoma-derived growth factor 1
    XP_001151101.1
188 aa
   LOC712918,  M.mulatta
putative teratocarcinoma-derived growth factor 2-like
    XP_001114010.1
182 aa
   TDGF1,  C.lupus
teratocarcinoma-derived growth factor 1
    XP_005633250.1
168 aa
   TDGF1,  B.taurus
teratocarcinoma-derived growth factor 1
    NP_001073827.1
181 aa
   LOC101906048,  B.taurus
putative teratocarcinoma-derived growth factor 3-like
    XP_005220011.1
181 aa
   Tdgf1,  M.musculus
teratocarcinoma-derived growth factor 1
    NP_035692.2
171 aa
   Tdgf1,  R.norvegicus
teratocarcinoma-derived growth factor 1
    XP_001056317.2
181 aa
   tdgf1.1,  X.tropicalis
teratocarcinoma-derived growth factor 1, member 1
    NP_001078829.1
146 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Forebrain defects.



Publications
Articles associated with genes and sequences of this homology group.

Expression and functional role of CRIPTO-1 in cutaneous melanoma.
De Luca A, et al. Br J Cancer 105, 1030-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CFC (pfam09443)
  Cripto_Frl-1_Cryptic (CFC).
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
NBD_sugar-kinase_HSP70_actin (cl17037)
  Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
NBD_sugar-kinase_HSP70_actin (cl17037)
  Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tdgf1 includes H.sapiens TDGF1 and R.norvegicus Tdgf1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 4 species)
Amniota - vertebrates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

 

 

 

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