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HomoloGene:20092. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ITGB2,  H.sapiens
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    NP_001120963.1
769 aa
   ITGB2,  P.troglodytes
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    NP_001029294.1
769 aa
   ITGB2,  C.lupus
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    XP_005639033.1
773 aa
   ITGB2,  B.taurus
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    NP_786975.1
769 aa
   Itgb2,  M.musculus
integrin beta 2
    NP_032430.2
770 aa
   Itgb2,  R.norvegicus
integrin, beta 2
    NP_001032869.2
768 aa
   ITGB2,  G.gallus
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    NP_990582.1
772 aa
   itgb2,  X.tropicalis
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    XP_002936570.2
771 aa
   itgb2,  D.rerio
integrin, beta 2
    XP_686012.3
768 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Leukocyte adhesion deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Innate immunity gene polymorphisms and the risk of colorectal neoplasia.
Chang CM, et al. Carcinogenesis 34, 2512-20 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Integrin_b_cyt (pfam08725)
  Integrin beta cytoplasmic domain.
Integrin_beta (pfam00362)
  Integrin, beta chain.
Integrin_B_tail (pfam07965)
  Integrin beta tail domain.
Integrin_B_tail (pfam07965)
  Integrin beta tail domain.
VESA1_N (pfam12785)
  Variant erythrocyte surface antigen-1.
Integrin_beta (cl17693)
  Integrin, beta chain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Itgb2 includes H.sapiens ITGB2 and R.norvegicus Itgb2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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