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HomoloGene:2331. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   SNTA1,  H.sapiens
syntrophin, alpha 1
505 aa
   SNTA1,  P.troglodytes
syntrophin, alpha 1
505 aa
   SNTA1,  M.mulatta
syntrophin, alpha 1
505 aa
   SNTA1,  C.lupus
syntrophin, alpha 1
500 aa
   SNTA1,  B.taurus
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
505 aa
   Snta1,  M.musculus
syntrophin, acidic 1
499 aa
   Snta1,  R.norvegicus
syntrophin, alpha 1
499 aa
   snta1,  X.tropicalis
syntrophin, alpha 1
473 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Long QT syndrome 12.

Articles associated with genes and sequences of this homology group.

Role of electrostatic interactions in PDZ domain ligand recognition.
Harris BZ, et al. Biochemistry 42, 2797-805 (2003).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PH-like (cl00273)
  Pleckstrin homology-like domain.
PH (pfam00169)
  PH domain.
PH-like (cl17171)
  Pleckstrin homology-like domain.
PDZ (cl00117)
  PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
PH-like (cl17171)
  Pleckstrin homology-like domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Snta1 includes H.sapiens SNTA1 and R.norvegicus Snta1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)




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