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HomoloGene:7412. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MC3R,  H.sapiens
melanocortin 3 receptor
    NP_063941.3
323 aa
   MC3R,  P.troglodytes
melanocortin 3 receptor
    XP_525362.1
360 aa
   LOC698439,  M.mulatta
melanocortin receptor 3-like
    XP_001091108.1
354 aa
   MC3R,  C.lupus
melanocortin 3 receptor
    NP_001128596.1
323 aa
   MC3R,  B.taurus
melanocortin 3 receptor
    XP_002692472.1
323 aa
   Mc3r,  M.musculus
melanocortin 3 receptor
    NP_032587.1
323 aa
   Mc3r,  R.norvegicus
melanocortin 3 receptor
    NP_001020441.3
323 aa
   LOC100857164,  G.gallus
melanocortin receptor 3-like
    XP_004947293.1
325 aa
   mc3r,  X.tropicalis
melanocortin 3 receptor
    XP_002935436.1
329 aa
   mc3r,  D.rerio
melanocortin 3 receptor
    NP_851303.1
327 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Obesity, severe, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Melanocortin-3 receptor regulates the normal fasting response.
Renquist BJ, et al. Proc Natl Acad Sci U S A 109, E1489-98 (2012).
Melanocortin-3 receptors are involved in adaptation to restricted feeding.
Begriche K, et al. Genes Brain Behav 11, 291-302 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mc3r includes H.sapiens MC3R and R.norvegicus Mc3r.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

 

 

 

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