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HomoloGene:72287. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   THEMIS,  H.sapiens
thymocyte selection associated
    NP_001158157.1
680 aa
   THEMIS,  P.troglodytes
thymocyte selection associated
    XP_003311524.1
680 aa
   THEMIS,  C.lupus
thymocyte selection associated
    XP_541237.4
653 aa
   THEMIS,  B.taurus
thymocyte selection associated
    NP_001091585.1
641 aa
   Themis,  M.musculus
thymocyte selection associated
    NP_848781.1
636 aa
   Themis,  R.norvegicus
thymocyte selection associated
    XP_006227737.1
631 aa
   THEMIS,  G.gallus
thymocyte selection associated
    XP_001232459.3
665 aa
   themis,  X.tropicalis
thymocyte selection associated
    XP_002940439.2
561 aa
   themis,  D.rerio
thymocyte selection associated
    XP_683025.3
675 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Themis imposes new law and order on positive selection.
Allen PM. Nat Immunol 10, 805-6 (2009).
Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes.
Patrick MS, et al. Proc Natl Acad Sci U S A 106, 16345-50 (2009).
A novel gene essential for the development of single positive thymocytes.
Kakugawa K, et al. Mol Cell Biol 29, 5128-35 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CABIT (pfam12736)
  Cell-cycle sustaining, positive selection.
CABIT (pfam12736)
  Cell-cycle sustaining, positive selection.
GVQW (pfam13900)
  Putative binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Themis includes H.sapiens THEMIS.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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