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HomoloGene:37251. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   AGXT,  H.sapiens
alanine-glyoxylate aminotransferase
    NP_000021.1
392 aa
   AGXT,  P.troglodytes
alanine-glyoxylate aminotransferase
    XP_003309627.2
504 aa
   AGXT,  M.mulatta
alanine-glyoxylate aminotransferase
    XP_001090301.2
414 aa
   LOC100855679,  C.lupus
serine--pyruvate aminotransferase, mitochondrial-like
    XP_003639939.1
414 aa
   LOC607355,  C.lupus
serine--pyruvate aminotransferase, mitochondrial-like
    XP_848328.2
422 aa
   AGXT,  B.taurus
alanine-glyoxylate aminotransferase
    NP_001095825.1
414 aa
   Agxt,  M.musculus
alanine-glyoxylate aminotransferase
    NP_057911.2
414 aa
   Agxt,  R.norvegicus
alanine-glyoxylate aminotransferase
    NP_085914.2
414 aa
   AGXT,  G.gallus
alanine-glyoxylate aminotransferase
    XP_003641783.2
416 aa
   agxt,  X.tropicalis
alanine-glyoxylate aminotransferase
    NP_001006705.1
391 aa
   agxta,  D.rerio
alanine-glyoxylate aminotransferase a
    NP_001002331.1
391 aa
   agxtb,  D.rerio
alanine-glyoxylate aminotransferase b
    NP_998327.1
423 aa
   Spat,  D.melanogaster
Serine pyruvate aminotransferase
    NP_511062.1
394 aa
   AgaP_AGAP003490,  A.gambiae
AgaP_AGAP003490
    XP_309676.3
396 aa
   T14D7.1,  C.elegans
T14D7.1
    NP_495885.1
405 aa
   AGX1,  S.cerevisiae
AGX1
    NP_116623.1
385 aa
   KLLA0F08954g,  K.lactis
KLLA0F08954g
    XP_455487.1
367 aa
   MGG_02525,  M.oryzae
MGG_02525
    XP_003709335.1
437 aa
   NCU01821,  N.crassa
NCU01821
    XP_955918.1
446 aa
   AGT,  A.thaliana
AGT
    NP_178969.1
401 aa
   Os08g0502700,  O.sativa
Os08g0502700
    NP_001062170.1
402 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hyperoxaluria, primary, type 1.



Publications
Articles associated with genes and sequences of this homology group.

Molecular insights into primary hyperoxaluria type 1 pathogenesis.
Cellini B, et al. Front Biosci (Landmark Ed) 17, 621-34 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AAT_I (cl00321)
  Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
AAT_I (cl18945)
  Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Agxt includes H.sapiens AGXT and R.norvegicus Agxt.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (43 transcripts, 35 species)
Liliopsida - monocots (11 transcripts, 8 species)
Coniferopsida - conifers (6 transcripts, 3 species)
Bryopsida - mosses (3 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (4 transcripts, 2 species)

Chordata
Actinopterygii - bony fishes (22 transcripts, 11 species)
Mammalia - mammals (11 transcripts, 10 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (16 transcripts, 10 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (18 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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