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HomoloGene:3882. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GRB10,  H.sapiens
growth factor receptor-bound protein 10
    NP_005302.3
594 aa
   GRB10,  P.troglodytes
growth factor receptor-bound protein 10
    XP_001154916.2
594 aa
   GRB10,  M.mulatta
growth factor receptor-bound protein 10
    XP_002803316.1
593 aa
   GRB10,  C.lupus
growth factor receptor-bound protein 10
    XP_849638.2
580 aa
   GRB10,  B.taurus
growth factor receptor-bound protein 10
    NP_001179515.1
529 aa
   Grb10,  M.musculus
growth factor receptor bound protein 10
    NP_034475.2
596 aa
   Grb10,  R.norvegicus
growth factor receptor bound protein 10
    NP_001102563.1
434 aa
   GRB10,  G.gallus
growth factor receptor-bound protein 10
    NP_001034371.1
596 aa
   grb10,  X.tropicalis
growth factor receptor-bound protein 10
    NP_001120881.1
576 aa
   grb10b,  D.rerio
growth factor receptor-bound protein 10b
    XP_005157930.1
595 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Grb10 interacts with Bim L and inhibits apoptosis.
Hu ZQ, et al. Mol Biol Rep 37, 3547-52 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
BPS (pfam08947)
  BPS (Between PH and SH2).
PH-like (cl00273)
  Pleckstrin homology-like domain.
UBQ (cl00155)
  Ubiquitin-like proteins.
SH2 (cl15255)
  Src homology 2 (SH2) domain.
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Grb10 includes H.sapiens GRB10 and R.norvegicus Grb10.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (9 transcripts, 4 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

 

 

 

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