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HomoloGene:11203. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MTMR14,  H.sapiens
myotubularin related protein 14
    NP_001070993.1
650 aa
   MTMR14,  P.troglodytes
myotubularin related protein 14
    XP_003309760.1
643 aa
   MTMR14,  M.mulatta
myotubularin related protein 14
    XP_001092278.2
714 aa
   MTMR14,  C.lupus
myotubularin related protein 14
    XP_541783.2
648 aa
   MTMR14,  B.taurus
myotubularin related protein 14
    NP_001093834.1
597 aa
   Mtmr14,  M.musculus
myotubularin related protein 14
    NP_081125.2
648 aa
   Mtmr14,  R.norvegicus
myotubularin related protein 14
    NP_001101350.1
648 aa
   mtmr14,  X.tropicalis
myotubularin related protein 14
    NP_001090713.1
626 aa
   mtmr14,  D.rerio
myotubularin related protein 14
    XP_002662433.2
630 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Centronuclear myopathy, autosomal, modifier of.



Publications
Articles associated with genes and sequences of this homology group.

MIP/MTMR14 and muscle aging.
Powers SK & Reid MB. Aging (Albany NY) 2, 538 (2010).
Protein tyrosine phosphatases in the human genome.
Alonso A, et al. Cell 117, 699-711 (2004).
The role of MTMR14 in autophagy and in muscle disease.
Gibbs EM, et al. Autophagy 6, 819-20 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Y_phosphatase_m (pfam13849)
  Myotubularin Y_phosphatase-like.
Myotub-related (pfam06602)
  Myotubularin-like phosphatase domain.
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mtmr14 includes H.sapiens MTMR14 and R.norvegicus Mtmr14.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (10 transcripts, 7 species)
Mammalia - mammals (9 transcripts, 9 species)
Aves - birds (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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