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HomoloGene:73894. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   CYP2B6,  H.sapiens
cytochrome P450, family 2, subfamily B, polypeptide 6
491 aa
   LOC456052,  P.troglodytes
cytochrome P450 2B6-like
491 aa
   CYP2B6,  M.mulatta
cytochrome P450, family 2, subfamily B, polypeptide 6
491 aa
   CYP2B6,  C.lupus
cytochrome P450 2B11
494 aa
   CYP2B6,  B.taurus
cytochrome P450 subfamily 2B
442 aa
   Cyp2b10,  M.musculus
cytochrome P450, family 2, subfamily b, polypeptide 10
491 aa
   Cyp2b1,  R.norvegicus
cytochrome P450, family 2, subfamily b, polypeptide 1
491 aa
   Cyp2b2,  R.norvegicus
cytochrome P450, family 2, subfamily b, polypeptide 2
499 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Would a CYP2B6 test help HIV patients being treated with efavirenz?
Sukasem C & Sungkanuparph S. Pharmacogenomics 14, 999-1001 (2013).
Influence of the CYP2B6 polymorphism on the pharmacokinetics of mitotane.
D'Avolio A, et al. Pharmacogenet Genomics 23, 293-300 (2013).
Haplotypes frequencies of CYP2B6 in Malaysia.
Musa N, et al. J Postgrad Med 58, 235-41 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
p450 (pfam00067)
  Cytochrome P450.
p450 (cl12078)
  Cytochrome P450.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cyp2b10 includes H.sapiens CYP2B6 and R.norvegicus Cyp2b2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (17 transcripts, 11 species)

Maxillopoda - crustaceans (1 transcript, 1 species)




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