Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:69035. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   RAC1,  H.sapiens
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    NP_061485.1
211 aa
   RAC1,  P.troglodytes
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    NP_001233310.1
192 aa
   LOC717755,  M.mulatta
40S ribosomal protein S0-like
    XP_001109586.2
369 aa
   RAC1,  C.lupus
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    NP_001003274.1
192 aa
   RAC1,  B.taurus
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    NP_776588.1
192 aa
   Rac1,  M.musculus
RAS-related C3 botulinum substrate 1
    NP_033033.1
192 aa
   Rac1,  R.norvegicus
ras-related C3 botulinum toxin substrate 1
    NP_599193.1
192 aa
   RAC1,  G.gallus
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    NP_990348.1
192 aa
   rac1,  X.tropicalis
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    NP_001004840.1
192 aa
   rac1a,  D.rerio
ras-related C3 botulinum toxin substrate 1a (rho family, small GTP binding protein Rac1)
    NP_956065.1
192 aa
   Rac1,  D.melanogaster
Rac1
    NP_476950.1
192 aa
   Rac2,  D.melanogaster
Rac2
    NP_001261517.1
192 aa
   AgaP_AGAP005445,  A.gambiae
AgaP_AGAP005445
    XP_315449.4
192 aa
   ROP1,  A.thaliana
ROP1
    NP_190698.1
197 aa
   ARAC1,  A.thaliana
ARAC1
    NP_179371.1
197 aa
   RAC6,  A.thaliana
RAC6
    NP_195320.1
197 aa
   Os02g0120800,  O.sativa
Os02g0120800
    NP_001045712.1
197 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Rac1 pathway mediates stretch response in pulmonary alveolar epithelial cells.
Dipaolo BC, et al. Am J Physiol Lung Cell Mol Physiol 305, L141-53 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RPS2 (cl00315)
  Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of ...
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rac1 includes H.sapiens RAC1 and R.norvegicus Rac1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (136 transcripts, 35 species)
Coniferopsida - conifers (15 transcripts, 3 species)
Liliopsida - monocots (12 transcripts, 7 species)
Bryopsida - mosses (3 transcripts, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chordata
Actinopterygii - bony fishes (23 transcripts, 10 species)
Mammalia - mammals (22 transcripts, 15 species)
Ascidiacea - tunicates (11 transcripts, 3 species)
Cephalochordata - lancelets (4 transcripts, 1 species)
Aves - birds (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (5 transcripts, 4 species)
Arachnida - arachnids (3 transcripts, 2 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (6 transcripts, 2 species)
Turbellaria - flatworms (3 transcripts, 1 species)

Porifera
Demospongiae - sponges (5 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (5 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (5 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (5 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (3 transcripts, 2 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

Write to the Help Desk