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HomoloGene:4088. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NFIC,  H.sapiens
nuclear factor I/C (CCAAT-binding transcription factor)
    NP_001231931.1
508 aa
   NFIC,  M.mulatta
nuclear factor I/C (CCAAT-binding transcription factor)
    XP_001117899.2
619 aa
   NFIC,  C.lupus
nuclear factor I/C (CCAAT-binding transcription factor)
    XP_542179.4
506 aa
   NFIC,  B.taurus
nuclear factor I/C (CCAAT-binding transcription factor)
    NP_001019745.1
428 aa
   Nfic,  M.musculus
nuclear factor I/C
    NP_032714.1
439 aa
   Nfic,  R.norvegicus
nuclear factor I/C
    NP_113755.1
439 aa
   NFIC,  G.gallus
nuclear factor I/C (CCAAT-binding transcription factor)
    NP_990602.1
510 aa
   nfic,  X.tropicalis
nuclear factor I/C (CCAAT-binding transcription factor)
    XP_004911089.1
509 aa
   LOC100005568,  D.rerio
novel protein similar to vertebrate nuclear factor I/C (CCAAT-binding transcription factor) (NFIC)
    XP_005166996.1
506 aa
   NFI,  A.gambiae
NFI
    XP_311086.2
254 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Tissue- and cell-specific alternative splicing of NFIC.
Lamani E, et al. Cells Tissues Organs 189, 105-10 (2009).
CTF5--a new transcriptional activator of the NFI/CTF family.
Wenzelides S, et al. Nucleic Acids Res 24, 2416-21 (1996).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CTF_NFI (pfam00859)
  CTF/NF-I family transcription modulation region.
NfI_DNAbd_pre-N (pfam10524)
  Nuclear factor I protein pre-N-terminus.
MH1 (pfam03165)
  MH1 domain.
MH1 (cl00055)
  N-terminal Mad Homology 1 (MH1) domain.
MH1 (cl00055)
  N-terminal Mad Homology 1 (MH1) domain.
RPE65 (cl10080)
  Retinal pigment epithelial membrane protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nfic includes H.sapiens NFIC and R.norvegicus Nfic.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Amphibia - amphibians (3 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

 

 

 

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