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HomoloGene:56129. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MAPRE1,  H.sapiens
microtubule-associated protein, RP/EB family, member 1
    NP_036457.1
268 aa
   MAPRE1,  P.troglodytes
microtubule-associated protein, RP/EB family, member 1
    XP_001154462.2
268 aa
   MAPRE1,  M.mulatta
microtubule-associated protein, RP/EB family, member 1
    XP_001107004.2
268 aa
   MAPRE1,  C.lupus
microtubule-associated protein, RP/EB family, member 1
    NP_001238875.1
268 aa
   MAPRE1,  B.taurus
microtubule-associated protein, RP/EB family, member 1
    NP_001068802.1
268 aa
   Mapre1,  M.musculus
microtubule-associated protein, RP/EB family, member 1
    NP_031922.1
268 aa
   Mapre1,  R.norvegicus
microtubule-associated protein, RP/EB family, member 1
    NP_612518.2
268 aa
   MAPRE1,  G.gallus
microtubule-associated protein, RP/EB family, member 1
    NP_001026031.1
258 aa
   mapre1,  X.tropicalis
microtubule-associated protein, RP/EB family, member 1
    NP_989115.1
269 aa
   mapre1b,  D.rerio
microtubule-associated protein, RP/EB family, member 1b
    NP_998805.1
258 aa
   BIM1,  S.cerevisiae
BIM1
    NP_010932.1
344 aa
   KLLA0B11550g,  K.lactis
KLLA0B11550g
    XP_452044.1
276 aa
   AGOS_AAR024W,  E.gossypii
AGOS_AAR024W
    NP_982565.1
322 aa
   mal3,  S.pombe
mal3
    NP_593678.1
308 aa
   MGG_05427,  M.oryzae
MGG_05427
    XP_003710287.1
247 aa
   NCU00243,  N.crassa
NCU00243
    XP_957714.2
273 aa
   EB1C,  A.thaliana
EB1C
    NP_201528.1
329 aa
   Os10g0498900,  O.sativa
Os10g0498900
    NP_001064972.1
332 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

EB1 regulates microtubule dynamics and tubulin sheet closure in vitro.
Vitre B, et al. Nat Cell Biol 10, 415-21 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EB1 (pfam03271)
  EB1-like C-terminal motif.
CH (pfam00307)
  Calponin homology (CH) domain.
EB1 (pfam03271)
  EB1-like C-terminal motif.
CH (cl00030)
  Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mapre1 includes H.sapiens MAPRE1 and R.norvegicus Mapre1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (20 transcripts, 9 species)
Mammalia - mammals (17 transcripts, 16 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (3 transcripts, 3 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (3 transcripts, 1 species)
Trematoda - flatworms (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (25 transcripts, 20 species)
Liliopsida - monocots (8 transcripts, 7 species)
Coniferopsida - conifers (5 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (4 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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