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HomoloGene:38160. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PRKAB1,  H.sapiens
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    NP_006244.2
270 aa
   PRKAB1,  P.troglodytes
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    NP_001233530.1
270 aa
   PRKAB1,  M.mulatta
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    XP_001085323.1
270 aa
   PRKAB1,  C.lupus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    XP_543421.2
270 aa
   PRKAB1,  B.taurus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    NP_001019729.1
270 aa
   Prkab1,  M.musculus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    NP_114075.1
270 aa
   Prkab1,  R.norvegicus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    NP_114182.1
270 aa
   PRKAB1,  G.gallus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    NP_001035001.1
273 aa
   prkab1,  X.tropicalis
protein kinase, AMP-activated, beta 1 non-catalytic subunit
    XP_002932123.1
265 aa
   prkab1a,  D.rerio
protein kinase, AMP-activated, beta 1 non-catalytic subunit, a
    NP_001002632.1
268 aa
   alc,  D.melanogaster
alicorn
    NP_610460.1
341 aa
   AgaP_AGAP008195,  A.gambiae
AgaP_AGAP008195
    XP_317273.3
297 aa
   amk2,  S.pombe
amk2
    NP_588485.1
298 aa
   MGG_06930,  M.oryzae
MGG_06930
    XP_003709669.1
479 aa
   NCU03837,  N.crassa
NCU03837
    XP_960596.1
481 aa
   AT4G16360,  A.thaliana
AT4G16360
    NP_001031650.2
258 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

A role for AMPK in increased insulin action after serum starvation.
Ching JK, et al. Am J Physiol Cell Physiol 299, C1171-9 (2010).
The role of AMP-activated protein kinase in the cardiovascular system.
Nagata D & Hirata Y. Hypertens Res 33, 22-8 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AMPKBI (pfam04739)
  5'-AMP-activated protein kinase beta subunit, interation domain.
AMPKBI (cl08426)
  5'-AMP-activated protein kinase beta subunit, interation domain.
E_set (cl09101)
  Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkab1 includes H.sapiens PRKAB1 and R.norvegicus Prkab1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (9 transcripts, 7 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (17 transcripts, 13 species)
Arachnida - arachnids (3 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (40 transcripts, 27 species)
Bryopsida - mosses (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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