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HomoloGene:23133. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NLGN3,  H.sapiens
neuroligin 3
    NP_851820.1
848 aa
   NLGN3,  P.troglodytes
neuroligin 3
    XP_529033.2
818 aa
   NLGN3,  C.lupus
neuroligin 3
    XP_005641518.1
848 aa
   NLGN3,  B.taurus
neuroligin 3
    NP_001068972.1
808 aa
   Nlgn3,  M.musculus
neuroligin 3
    NP_766520.2
825 aa
   Nlgn3,  R.norvegicus
neuroligin 3
    NP_599163.2
848 aa
   NLGN3,  G.gallus
neuroligin 3
    NP_001166992.1
813 aa
   nlgn3,  X.tropicalis
neuroligin 3
    NP_001165298.1
803 aa
   nlgn3a,  D.rerio
neuroligin 3a
    NP_001159804.1
815 aa
   CG34139,  D.melanogaster
CG34139
    NP_001036730.2
1280 aa
   AgaP_AGAP003115,  A.gambiae
AgaP_AGAP003115
    XP_312799.5
1001 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Autism, susceptibility to, X-linked-1.
Asperger syndrome, susceptibility to, X-linked-1.



Publications
Articles associated with genes and sequences of this homology group.

The making of neurexins.
Missler M, et al. J Neurochem 71, 1339-47 (1998).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
COesterase (pfam00135)
  Carboxylesterase family.
Aes (COG0657)
  Esterase/lipase [Lipid metabolism].
Esterase_lipase (cl19094)
  Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nlgn3 includes H.sapiens NLGN3 and R.norvegicus Nlgn3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 10 species)
Actinopterygii - bony fishes (12 transcripts, 6 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)
Arachnida - arachnids (2 transcripts, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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