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HomoloGene:456. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SFTPB,  H.sapiens
surfactant protein B
    NP_000533.3
393 aa
   SFTPB,  P.troglodytes
surfactant protein B
    XP_001168379.2
317 aa
   SFTPB,  M.mulatta
surfactant protein B
    XP_001089841.1
381 aa
   SFTPB,  C.lupus
surfactant protein B
    XP_005630540.1
361 aa
   SFTPB,  B.taurus
surfactant protein B
    NP_001068779.1
373 aa
   Sftpb,  M.musculus
surfactant associated protein B
    NP_001269000.1
354 aa
   Sftpb,  R.norvegicus
surfactant protein B
    NP_620197.1
376 aa
   sftpb,  X.tropicalis
surfactant protein B
    XP_002932589.2
391 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Pulmonary alveolar proteinosis, congenital.
Surfactant metabolism dysfunction, pulmonary, 1.



Publications
Articles associated with genes and sequences of this homology group.

Amplification of steroid-mediated SP-B expression by physiological levels of caffeine.
Fehrholz M, et al. Am J Physiol Lung Cell Mol Physiol 306, L101-9 (2014).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SapB_2 (pfam03489)
  Saposin-like type B, region 2.
SapB_1 (pfam05184)
  Saposin-like type B, region 1.
SapA (cl02494)
  Saposin A-type domain.
SapB (smart00741)
  Saposin (B) Domains.
SapB_2 (pfam03489)
  Saposin-like type B, region 2.
SapB_1 (pfam05184)
  Saposin-like type B, region 1.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sftpb includes H.sapiens SFTPB and R.norvegicus Sftpb.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (4 transcripts, 4 species)

 

 

 

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