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HomoloGene:30955. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CYP19A1,  H.sapiens
cytochrome P450, family 19, subfamily A, polypeptide 1
    NP_112503.1
503 aa
   CYP19A1,  P.troglodytes
cytochrome P450, family 19, subfamily A, polypeptide 1
    XP_001169497.1
503 aa
   CYP19A1,  M.mulatta
cytochrome P450, family 19, subfamily A, polypeptide 1
    XP_001082665.2
503 aa
   CYP19A1,  C.lupus
cytochrome P450, family 17, subfamily A, polypeptide 1
    NP_001008715.1
503 aa
   CYP19A1,  B.taurus
cytochrome P450, family 19, subfamily A, polypeptide 1
    NP_776730.1
503 aa
   Cyp19a1,  M.musculus
cytochrome P450, family 19, subfamily a, polypeptide 1
    NP_031836.1
503 aa
   Cyp19a1,  R.norvegicus
cytochrome P450, family 19, subfamily a, polypeptide 1
    NP_058781.2
503 aa
   CYP19A1,  G.gallus
cytochrome P450, family 19, subfamily A, polypeptide 1
    NP_001001761.1
507 aa
   cyp19a1,  X.tropicalis
cytochrome P450, family 19, subfamily A, polypeptide 1
    NP_001090630.1
500 aa
   cyp19a1b,  D.rerio
cytochrome P450, family 19, subfamily A, polypeptide 1b
    NP_571717.1
511 aa
   cyp19a1a,  D.rerio
cytochrome P450, family 19, subfamily A, polypeptide 1a
    NP_571229.2
509 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Aromatase deficiency.
Pseudohermaphroditism, female, due to placental aromatase deficiency.
Aromatase excess syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Aromatase deficiency, a rare syndrome: case report.
Baykan EK, et al. J Clin Res Pediatr Endocrinol 5, 129-32 (2013).
CYP19A1 gene polymorphisms and risk of lung cancer.
Zhang J, et al. J Int Med Res 41, 735-42 (2013).
Aromatase variants modify risk for Alzheimer's disease in a multiethnic female cohort.
Janicki SC, et al. Dement Geriatr Cogn Disord 35, 340-6 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
p450 (pfam00067)
  Cytochrome P450.
p450 (cl12078)
  Cytochrome P450.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cyp19a1 includes H.sapiens CYP19A1 and R.norvegicus Cyp19a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (18 transcripts, 10 species)
Mammalia - mammals (13 transcripts, 13 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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