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HomoloGene:3272. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   EPS8,  H.sapiens
epidermal growth factor receptor pathway substrate 8
    NP_004438.3
822 aa
   EPS8,  P.troglodytes
epidermal growth factor receptor pathway substrate 8
    XP_003313572.1
822 aa
   EPS8,  M.mulatta
epidermal growth factor receptor pathway substrate 8
    XP_002798566.1
822 aa
   EPS8,  C.lupus
epidermal growth factor receptor pathway substrate 8
    XP_005637165.1
821 aa
   EPS8,  B.taurus
epidermal growth factor receptor pathway substrate 8
    XP_005207053.1
836 aa
   Eps8,  M.musculus
epidermal growth factor receptor pathway substrate 8
    NP_001258516.1
847 aa
   Eps8,  R.norvegicus
epidermal growth factor receptor pathway substrate 8
    XP_006237645.1
822 aa
   EPS8,  G.gallus
epidermal growth factor receptor pathway substrate 8
    XP_004938019.1
828 aa
   eps8,  X.tropicalis
epidermal growth factor receptor pathway substrate 8
    NP_001072508.1
788 aa
   eps8,  D.rerio
epidermal growth factor receptor pathway substrate 8
    NP_956536.1
804 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Eps8 promotes cellular growth of human malignant gliomas.
Ding X, et al. Oncol Rep 29, 697-703 (2013).
Expression of Eps8 correlates with poor survival in oral squamous cell carcinoma.
Chu PY, et al. Asia Pac J Clin Oncol 8, e77-81 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SAM_superfamily (cl15755)
  SAM (Sterile alpha motif ).
SH3 (cl17036)
  Src Homology 3 domain superfamily.
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Eps8 includes H.sapiens EPS8 and R.norvegicus Eps8.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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