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HomoloGene:18748. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FOXK2,  H.sapiens
forkhead box K2
    NP_004505.2
660 aa
   FOXK2,  P.troglodytes
forkhead box K2
    XP_003315834.1
646 aa
   FOXK2,  M.mulatta
forkhead box K2
    XP_001114082.2
617 aa
   FOXK2,  C.lupus
forkhead box K2
    XP_005642232.1
915 aa
   FOXK2,  B.taurus
forkhead box K2
    XP_002696174.3
603 aa
   Foxk2,  M.musculus
forkhead box K2
    NP_001074401.2
651 aa
   FOXK2,  G.gallus
forkhead box K2
    XP_425369.4
670 aa
   foxk2,  X.tropicalis
forkhead box K2
    NP_001135634.1
645 aa
   si:ch211-262e15.1,  D.rerio
si:ch211-262e15.1
    XP_001922856.1
597 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

FOXK2 transcription factor is a novel G/T-mismatch DNA binding protein.
Fujii Y & Nakamura M. J Biochem 147, 705-9 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FHA (cl00062)
  Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
FH (cl00061)
  Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA ...
FHA (cl00062)
  Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Foxk2 includes H.sapiens FOXK2 and R.norvegicus Foxk2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (7 transcripts, 7 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

 

 

 

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