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HomoloGene:56940. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ATP13A2,  H.sapiens
ATPase type 13A2
    NP_001135445.1
1175 aa
   ATP13A2,  P.troglodytes
ATPase type 13A2
    XP_513111.3
893 aa
   ATP13A2,  M.mulatta
ATPase type 13A2
    XP_001087655.2
1179 aa
   ATP13A2,  C.lupus
ATPase type 13A2
    XP_005618006.1
1170 aa
   ATP13A2,  B.taurus
ATPase type 13A2
    NP_001179200.1
1171 aa
   Atp13a2,  M.musculus
ATPase type 13A2
    NP_083373.2
1169 aa
   Atp13a2,  R.norvegicus
ATPase type 13A2
    NP_001166903.1
1145 aa
   atp13a2,  D.rerio
ATPase type 13A2
    NP_001073506.1
1170 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Kufor-Rakeb syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Hypoxia regulation of ATP13A2 (PARK9) gene transcription.
Xu Q, et al. J Neurochem 122, 251-9 (2012).
ATP13A2 (PARK9) polymorphisms influence the neurotoxic effects of manganese.
Rentschler G, et al. Neurotoxicology 33, 697-702 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Cation_ATPase_N (pfam00690)
  Cation transporter/ATPase, N-terminus.
HAD_like (cl11391)
  Haloacid Dehalogenase-like Hydrolases.
E1-E2_ATPase (pfam00122)
  E1-E2 ATPase.
P5-ATPase (pfam12409)
  P5-type ATPase cation transporter.
Hydrolase_like2 (pfam13246)
  Putative hydrolase of sodium-potassium ATPase alpha subunit.
COG4087 (COG4087)
  Soluble P-type ATPase [General function prediction only].
E1-E2_ATPase (pfam00122)
  E1-E2 ATPase.
P5-ATPase (pfam12409)
  P5-type ATPase cation transporter.
Hydrolase_like2 (pfam13246)
  Putative hydrolase of sodium-potassium ATPase alpha subunit.
Cation_ATPase_N (cl02930)
  Cation transporter/ATPase, N-terminus.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atp13a2 includes H.sapiens ATP13A2 and R.norvegicus Atp13a2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Aves - birds (3 transcripts, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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