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HomoloGene:31164. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ZYX,  H.sapiens
zyxin
    NP_003452.1
572 aa
   ZYX,  P.troglodytes
zyxin
    XP_003318907.1
572 aa
   ZYX,  M.mulatta
zyxin
    XP_001091405.1
572 aa
   ZYX,  C.lupus
zyxin
    XP_005629790.1
457 aa
   ZYX,  B.taurus
zyxin
    NP_001071569.1
559 aa
   Zyx,  M.musculus
zyxin
    NP_035907.1
564 aa
   Zyx,  R.norvegicus
zyxin
    NP_446213.1
564 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

A zyxin-nectin interaction facilitates zyxin localization to cell-cell adhesions.
Gregory Call S, et al. Biochem Biophys Res Commun 415, 485-9 (2011).
Zyxin-mediated actin assembly is required for efficient wound closure.
Nguyen TN, et al. J Biol Chem 285, 35439-45 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LIM (cl02475)
  LIM is a small protein-protein interaction domain, containing two zinc fingers.
COG1615 (cl09133)
  Uncharacterized conserved protein [Function unknown].
LIM (cl02475)
  LIM is a small protein-protein interaction domain, containing two zinc fingers.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Zyx includes H.sapiens ZYX and R.norvegicus Zyx.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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