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HomoloGene:68058. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PON1,  H.sapiens
paraoxonase 1
    NP_000437.3
355 aa
   PON1,  P.troglodytes
paraoxonase 1
    XP_519211.2
355 aa
   PON1,  M.mulatta
paraoxonase 1
    XP_001095992.1
355 aa
   PON1,  C.lupus
paraoxonase 1
    XP_850219.1
355 aa
   PON1,  B.taurus
paraoxonase 1
    NP_001039734.1
355 aa
   Pon1,  M.musculus
paraoxonase 1
    NP_035264.2
355 aa
   Pon1,  R.norvegicus
paraoxonase 1
    NP_114466.1
355 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Coronary artery disease, susceptibility to.
Coronary artery spasm, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Paraoxonase 1 activities and genetic variation in childhood obesity.
Rupérez AI, et al. Br J Nutr 110, 1639-47 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Str_synth (pfam03088)
  Strictosidine synthase.
Str_synth (cl19733)
  Strictosidine synthase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pon1 includes H.sapiens PON1 and R.norvegicus Pon1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Amniota - vertebrates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

 

 

 

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