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HomoloGene:68229. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   HAL,  H.sapiens
histidine ammonia-lyase
    NP_002099.1
657 aa
   HAL,  P.troglodytes
histidine ammonia-lyase
    XP_509282.3
657 aa
   HAL,  M.mulatta
histidine ammonia-lyase
    XP_001107685.1
657 aa
   HAL,  C.lupus
histidine ammonia-lyase
    XP_532657.2
657 aa
   HAL,  B.taurus
histidine ammonia-lyase
    NP_001098910.1
657 aa
   Hal,  M.musculus
histidine ammonia lyase
    NP_034531.1
657 aa
   Hal,  R.norvegicus
histidine ammonia lyase
    NP_058855.1
657 aa
   HAL,  G.gallus
histidine ammonia-lyase
    NP_989735.1
660 aa
   hal.1,  X.tropicalis
histidine ammonia-lyase, gene 1
    NP_001120565.1
657 aa
   hal,  D.rerio
histidine ammonia-lyase
    NP_001082926.1
654 aa
   haly-1,  C.elegans
haly-1
    NP_509820.1
677 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Histidinemia.



Publications
Articles associated with genes and sequences of this homology group.

Soy protein, casein, and zein regulate histidase gene expression by modulating serum glucagon.
Tovar AR, et al. Am J Physiol Endocrinol Metab 283, E1016-22 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DUF3534 (pfam12053)
  Domain of unknown function (DUF3534).
Lyase_aromatic (pfam00221)
  Aromatic amino acid lyase.
Lyase_I_like (cl00013)
  Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hal includes H.sapiens HAL and R.norvegicus Hal.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (12 transcripts, 10 species)
Mammalia - mammals (8 transcripts, 6 species)
Amphibia - amphibians (5 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (3 transcripts, 2 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)
Liliopsida - monocots (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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