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HomoloGene:9252. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CD207,  H.sapiens
CD207 molecule, langerin
    NP_056532.4
328 aa
   CD207,  P.troglodytes
CD207 molecule, langerin
    XP_001144168.1
328 aa
   CD207,  M.mulatta
CD207 molecule, langerin
    XP_001100466.1
328 aa
   CD207,  B.taurus
CD207 molecule, langerin
    XP_002691267.1
329 aa
   Cd207,  M.musculus
CD207 antigen
    NP_659192.2
331 aa
   Cd207,  R.norvegicus
CD207 molecule, langerin
    XP_578352.4
332 aa
   LOC101731344,  X.tropicalis
C-type lectin domain family 4 member F-like
    XP_004918912.1
562 aa
   LOC100497637,  X.tropicalis
hepatic lectin-like
    XP_002933952.2
225 aa
   LOC100497788,  X.tropicalis
hepatic lectin-like
    XP_004917035.1
218 aa
   LOC100494969,  X.tropicalis
asialoglycoprotein receptor 1-like
    XP_004917036.1
280 aa
   LOC100489411,  X.tropicalis
hepatic lectin-like
    XP_002935458.1
281 aa
   LOC100489257,  X.tropicalis
C-type lectin domain family 4 member G-like
    XP_002935457.2
268 aa
   LOC101731294,  X.tropicalis
CD209 antigen-like
    XP_004919366.1
223 aa
   LOC101731348,  X.tropicalis
CD209 antigen-like
    XP_004919367.1
125 aa
   LOC101731040,  X.tropicalis
C-type lectin domain family 4 member G-like
    XP_004918908.1
308 aa
   LOC101731464,  X.tropicalis
CD209 antigen-like protein A-like
    XP_004919369.1
218 aa
   LOC100489737,  X.tropicalis
C-type lectin domain family 4 member G-like
    XP_002935460.1
241 aa
   LOC100487099,  X.tropicalis
putative leucine-rich repeat-containing protein DDB_G0290503-like
    XP_002935446.2
638 aa
   LOC100486681,  X.tropicalis
hepatic lectin-like
    XP_002935444.2
224 aa
   LOC101730852,  X.tropicalis
C-type lectin domain family 4 member K-like
    XP_004918906.1
343 aa
   LOC100486529,  X.tropicalis
hepatic lectin-like
    XP_002935442.2
202 aa
   LOC100487251,  X.tropicalis
hepatic lectin-like
    XP_002935447.2
211 aa
   LOC101734871,  X.tropicalis
hepatic lectin-like
    XP_004918896.1
232 aa
   LOC101731226,  X.tropicalis
hepatic lectin-like
    XP_004918911.1
280 aa
   LOC101730984,  X.tropicalis
uncharacterized LOC101730984
    XP_004918907.1
623 aa
   LOC100486950,  X.tropicalis
uncharacterized LOC100486950
    XP_002936690.2
435 aa
   LOC100498593,  X.tropicalis
uncharacterized LOC100498593
    XP_004915122.1
403 aa
   LOC101733395,  X.tropicalis
uncharacterized LOC101733395
    XP_004916525.1
978 aa
   LOC101730291,  X.tropicalis
uncharacterized LOC101730291
    XP_004914391.1
409 aa
   LOC101730257,  X.tropicalis
hepatic lectin-like
    XP_004918901.1
223 aa
   LOC101731101,  X.tropicalis
hepatic lectin-like
    XP_004918909.1
238 aa
   LOC100486944,  X.tropicalis
hepatic lectin-like
    XP_002935445.1
238 aa
   LOC101731168,  X.tropicalis
hepatic lectin-like
    XP_004918910.1
226 aa
   LOC101735287,  X.tropicalis
hepatic lectin-like
    XP_004918900.1
234 aa
   LOC101735116,  X.tropicalis
hepatic lectin-like
    XP_004918899.1
194 aa
   LOC101735054,  X.tropicalis
hepatic lectin-like
    XP_004918898.1
108 aa
   LOC100487836,  X.tropicalis
C-type lectin domain family 4 member M-like
    XP_002935448.1
383 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Birbeck granule deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Common polymorphisms in human langerin change specificity for glycan ligands.
Feinberg H, et al. J Biol Chem 288, 36762-71 (2013).
Langerhans cells down-regulate inflammation-driven alveolar bone loss.
Arizon M, et al. Proc Natl Acad Sci U S A 109, 7043-8 (2012).
Langerhans cells are negative regulators of the anti-Leishmania response.
Kautz-Neu K, et al. J Exp Med 208, 885-91 (2011).
Characterization of Langerin-expressing dendritic cell subsets in the normal cornea.
Hattori T, et al. Invest Ophthalmol Vis Sci 52, 4598-604 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Baculo_PEP_C (pfam04513)
  Baculovirus polyhedron envelope protein, PEP, C terminus.
RVT_1 (pfam00078)
  Reverse transcriptase (RNA-dependent DNA polymerase).
CHD5 (pfam04420)
  CHD5-like protein.
Myb_DNA-bind_5 (pfam13873)
  Myb/SANT-like DNA-binding domain.
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
SPEC (cl02488)
  Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
RT_like (cl02808)
  RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons, ...
TMF_TATA_bd (pfam12325)
  TATA element modulatory factor 1 TATA binding.
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cd207 includes H.sapiens CD207 and R.norvegicus Cd207.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (3 transcripts, 3 species)

 

 

 

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