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HomoloGene:76480. Gene conserved in Diptera Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   Ace,  D.melanogaster
Acetylcholine esterase
    NP_001163600.1
649 aa
   AgaP_AGAP000466,  A.gambiae
AgaP_AGAP000466
    XP_310628.3
645 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

D.melanogaster
Loss of function alleles are recessive lethal dying at end of embryonic stage; then ultrastructural observations of CNS in such mutants suggest neural-degenerative defects (FBrf0047827). Ace-minus tissues survive in mosaics unless enzyme absent from posterior midbrain; surviving mosaics have defective visual physiology, optomotor behavior or courtship, depending on location of mutant clone. Such clones associated with defective morphology or neuropil of various ganglia in central nervous system (FBrf0035219). (See FlyBase for complete description.)



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
COesterase (pfam00135)
  Carboxylesterase family.
Aes (COG0657)
  Esterase/lipase [Lipid metabolism].



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Arthropoda
Insecta - insects (9 transcripts, 8 species)
Arachnida - arachnids (1 transcript, 1 species)

 

 

 

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