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HomoloGene:3066. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   PYY,  H.sapiens
peptide YY
97 aa
   PYY,  P.troglodytes
peptide YY
97 aa
   PYY,  M.mulatta
peptide YY
97 aa
   PYY,  C.lupus
peptide YY
97 aa
   PYY,  B.taurus
peptide YY
97 aa
   Pyy,  M.musculus
peptide YY
98 aa
   Pyy,  R.norvegicus
peptide YY (mapped)
98 aa
   pyy,  X.tropicalis
peptide YY
99 aa
   pyya,  D.rerio
peptide YYa
97 aa
   pyyb,  D.rerio
peptide YYb
95 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.


Articles associated with genes and sequences of this homology group.

Role of peptide YY(3-36) in the satiety produced by gastric delivery of macronutrients in rats.
Reidelberger R, et al. Am J Physiol Endocrinol Metab 304, E944-50 (2013).
The role of peptide YY in gastrointestinal diseases and disorders (review).
El-Salhy M, et al. Int J Mol Med 31, 275-82 (2013).
Case of peptide-YY-producing strumal carcinoid of the ovary: a case report and review.
Takatori E, et al. J Obstet Gynaecol Res 38, 1266-70 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PAH (cl00111)
  Pancreatic Hormone domain, a regulator of pancreatic and gastrointestinal functions; neuropeptide Y (NPY)b, peptide YY (PYY), and pancreatic polypetide (PP) are closely related; propeptide is enzymatically cleaved to yield the mature active peptide with amidated C-terminal ends; receptor binding and activation functions may reside in the N- and C-termini respectively; occurs in neurons, intestinal endocrine cells, and pancreas; exist as monomers and dimers

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pyy includes H.sapiens PYY and R.norvegicus Pyy.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Actinopterygii - bony fishes (8 transcripts, 7 species)
Mammalia - mammals (6 transcripts, 6 species)
Amniota - vertebrates (1 transcript, 1 species)




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