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HomoloGene:20470. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GABRR1,  H.sapiens
gamma-aminobutyric acid (GABA) A receptor, rho 1
    NP_002033.2
479 aa
   GABRR1,  P.troglodytes
gamma-aminobutyric acid (GABA) A receptor, rho 1
    XP_527447.3
479 aa
   GABRR1,  M.mulatta
gamma-aminobutyric acid (GABA) A receptor, rho 1
    XP_001095237.2
480 aa
   GABRR1,  C.lupus
gamma-aminobutyric acid (GABA) A receptor, rho 1
    XP_005627682.1
462 aa
   GABRR1,  B.taurus
gamma-aminobutyric acid (GABA) A receptor, rho 1
    XP_002690251.3
392 aa
   Gabrr1,  M.musculus
gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
    NP_032101.3
480 aa
   Gabrr1,  R.norvegicus
gamma-aminobutyric acid (GABA) A receptor, rho 1
    NP_058987.2
480 aa
   GABRR1,  G.gallus
gamma-aminobutyric acid (GABA) receptor, rho 1
    XP_426190.2
478 aa
   LOC100497913,  X.tropicalis
gamma-aminobutyric acid receptor subunit rho-1-like
    XP_002940959.2
478 aa
   LOC100330554,  D.rerio
gamma-aminobutyric acid receptor subunit rho-1-like
    XP_002662272.2
517 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Nitric oxide potentiation of the homomeric ρ1 GABA(C) receptor function.
Gasulla J, et al. Br J Pharmacol 167, 1369-77 (2012).
Functional impact of serial deletions at the C-terminus of the human GABArho1 receptor.
Reyes-Ruiz JM, et al. Biochim Biophys Acta 1798, 1002-7 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Neur_chan_memb (pfam02932)
  Neurotransmitter-gated ion-channel transmembrane region.
Neur_chan_LBD (pfam02931)
  Neurotransmitter-gated ion-channel ligand binding domain.
Neur_chan_memb (pfam02932)
  Neurotransmitter-gated ion-channel transmembrane region.
Neur_chan_LBD (pfam02931)
  Neurotransmitter-gated ion-channel ligand binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gabrr1 includes H.sapiens GABRR1 and R.norvegicus Gabrr1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (14 transcripts, 6 species)
Mammalia - mammals (6 transcripts, 6 species)
Amphibia - amphibians (5 transcripts, 2 species)

 

 

 

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