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HomoloGene:838. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   VCAM1,  H.sapiens
vascular cell adhesion molecule 1
    NP_001069.1
739 aa
   VCAM1,  M.mulatta
vascular cell adhesion molecule 1
    XP_001107924.1
739 aa
   VCAM1,  C.lupus
vascular cell adhesion molecule 1
    NP_001003298.1
739 aa
   LOC534578,  B.taurus
vascular cell adhesion molecule 1-like
    NP_001094628.1
740 aa
   VCAM1,  B.taurus
vascular cell adhesion molecule 1
    NP_776909.1
739 aa
   Vcam1,  M.musculus
vascular cell adhesion molecule 1
    NP_035823.3
739 aa
   Vcam1,  R.norvegicus
vascular cell adhesion molecule 1
    NP_037021.1
739 aa
   vcam1,  D.rerio
vascular cell adhesion molecule 1
    NP_001077304.1
808 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Apelin retards the progression of diabetic nephropathy.
Day RT, et al. Am J Physiol Renal Physiol 304, F788-800 (2013).
Molecular pathways: VCAM-1 as a potential therapeutic target in metastasis.
Chen Q & Massagué J. Clin Cancer Res 18, 5520-5 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
I-set (pfam07679)
  Immunoglobulin I-set domain.
IGc2 (smart00408)
  Immunoglobulin C-2 Type.
IG (smart00409)
  Immunoglobulin.
IG_like (smart00410)
  Immunoglobulin like.
I-set (pfam07679)
  Immunoglobulin I-set domain.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Vcam1 includes H.sapiens VCAM1 and R.norvegicus Vcam1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 13 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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