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HomoloGene:1391. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

COL6A1,  H.sapiens
collagen, type VI, alpha 1
NP_001839.2
1028 aa
COL6A1,  P.troglodytes
collagen, type VI, alpha 1
XP_001158445.1
1028 aa
LOC721855,  M.mulatta
uncharacterized LOC721855
XP_001118050.2
2077 aa
COL6A1,  C.lupus
collagen, type VI, alpha 1
XP_003434049.2
1026 aa
COL6A1,  B.taurus
collagen, type VI, alpha 1
NP_001137337.1
1027 aa
Col6a1,  M.musculus
collagen, type VI, alpha 1
NP_034063.1
1025 aa
Col6a1,  R.norvegicus
collagen, type VI, alpha 1
XP_215375.5
1034 aa
COL6A1,  G.gallus
collagen, type VI, alpha 1
NP_990438.1
1019 aa
col6a1,  X.tropicalis
collagen, type VI, alpha 1
XP_002932077.2
1046 aa
col6a1,  D.rerio
collagen, type VI, alpha 1
XP_698253.3
1031 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Bethlem myopathy.
Ullrich congenital muscular dystrophy.
Ossification of the posterior longitudinal spinal ligaments.



Publications
Articles associated with genes and sequences of this homology group.

Adipocyte-derived endotrophin promotes malignant tumor progression.
Park J & Scherer PE. J Clin Invest 122, 4243-56 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
vWFA (cl00057)
  Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
vWFA (cl00057)
  Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Collagen (cl19732)
  Collagen triple helix repeat (20 copies).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Col6a1 includes H.sapiens COL6A1 and R.norvegicus Col6a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 14 species)
Actinopterygii - bony fishes (6 transcripts, 4 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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