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HomoloGene:133272. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CASP1,  H.sapiens
caspase 1, apoptosis-related cysteine peptidase
    NP_150634.1
404 aa
   LOC101058924,  P.troglodytes
caspase-1-like
    XP_003952059.1
311 aa
   CASP1,  M.mulatta
caspase 1, apoptosis-related cysteine peptidase
    XP_001094943.2
567 aa
   CASP4,  C.lupus
caspase 4, apoptosis-related cysteine peptidase
    NP_001003125.1
404 aa
   CASP1,  B.taurus
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
    XP_002692967.1
403 aa
   Casp1,  M.musculus
caspase 1
    NP_033937.2
402 aa
   Casp1,  R.norvegicus
caspase 1
    NP_036894.2
402 aa
   CASP1,  G.gallus
caspase 1, apoptosis-related cysteine peptidase
    XP_003642432.2
393 aa
   LOC100491605,  X.tropicalis
caspase-1-A-like
    XP_002935240.2
384 aa
   caspa,  D.rerio
caspase a
    NP_571580.1
383 aa
   zgc:171731,  D.rerio
zgc:171731
    NP_001103182.1
446 aa
   si:ch211-233g6.8,  D.rerio
si:ch211-233g6.8
    XP_003197824.1
404 aa
   caspbl,  D.rerio
caspase b, like
    NP_001139064.1
409 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Pyrin_ASC-like (cd08321)
  Pyrin Death Domain found in ASC.
CARD_CASP1-like (cd08325)
  Caspase activation and recruitment domain found in Caspase-1 and related proteins.
DD_superfamily (cl14633)
  The Death Domain Superfamily of protein-protein interaction domains.
CASc (cl00042)
  Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
DD (cl14633)
  Death Domain Superfamily of protein-protein interaction domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Casp1 includes H.sapiens CASP1 and R.norvegicus Casp1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)

 

 

 

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