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HomoloGene:14452. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CCNE1,  H.sapiens
cyclin E1
    NP_001229.1
410 aa
   CCNE1,  P.troglodytes
cyclin E1
    XP_512559.4
411 aa
   CCNE1,  M.mulatta
cyclin E1
    XP_001084995.1
410 aa
   CCNE1,  C.lupus
cyclin E1
    XP_005616959.1
386 aa
   CCNE1,  B.taurus
cyclin E1
    NP_001179705.1
411 aa
   Ccne1,  M.musculus
cyclin E1
    NP_031659.2
408 aa
   Ccne1,  R.norvegicus
cyclin E1
    NP_001094291.1
411 aa
   CCNE1,  G.gallus
cyclin E1
    NP_001026529.1
407 aa
   ccne1,  X.tropicalis
cyclin E1
    NP_001016328.1
408 aa
   ccne1,  D.rerio
cyclin E1
    NP_571070.1
410 aa
   CycE,  D.melanogaster
Cyclin E
    NP_476960.1
602 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cyclin E1 is amplified and overexpressed in osteosarcoma.
Lockwood WW, et al. J Mol Diagn 13, 289-96 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Cyclin_C (pfam02984)
  Cyclin, C-terminal domain.
CYCLIN (cl00050)
  Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
CYCLIN (cl00050)
  Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ccne1 includes H.sapiens CCNE1 and R.norvegicus Ccne1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (10 transcripts, 7 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 8 species)
Arachnida - arachnids (2 transcripts, 2 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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