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HomoloGene:7863. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NFKBIA,  H.sapiens
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    NP_065390.1
317 aa
   NFKBIA,  P.troglodytes
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    XP_522823.2
317 aa
   NFKBIA,  M.mulatta
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    XP_001087842.1
317 aa
   NFKBIA,  C.lupus
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    XP_537413.3
314 aa
   NFKBIA,  B.taurus
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    NP_001039333.1
314 aa
   Nfkbia,  M.musculus
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
    NP_035037.2
314 aa
   Nfkbia,  R.norvegicus
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    NP_001099190.2
314 aa
   NFKBIA,  G.gallus
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    NP_001001472.2
318 aa
   nfkbia,  X.tropicalis
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    NP_001004851.1
315 aa
   nfkbiab,  D.rerio
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
    NP_955923.1
312 aa
   nfkbiaa,  D.rerio
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
    NP_998349.1
305 aa
   cact,  D.melanogaster
cactus
    NP_001260496.1
500 aa
   CACT,  A.gambiae
CACT
    XP_317542.4
377 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Ectodermal dysplasia, anhidrotic, with T-cell immunodeficiency.



Publications
Articles associated with genes and sequences of this homology group.

IκBα is not required for axon initial segment assembly.
Buffington SA, et al. Mol Cell Neurosci 50, 1-9 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ank (pfam00023)
  Ankyrin repeat.
Ank_5 (pfam13857)
  Ankyrin repeats (many copies).
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nfkbia includes H.sapiens NFKBIA and R.norvegicus Nfkbia.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 14 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 5 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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