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HomoloGene:645. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GRIN2A,  H.sapiens
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
NP_001127879.1
1464 aa
GRIN2A,  P.troglodytes
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
NP_001029361.1
1464 aa
LOC100429880,  M.mulatta
glutamate [NMDA] receptor subunit epsilon-1-like
XP_002802440.1
1145 aa
GRIN2A,  C.lupus
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
XP_547132.2
1464 aa
Grin2a,  M.musculus
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
NP_032196.2
1464 aa
Grin2a,  R.norvegicus
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
NP_036705.3
1464 aa
GRIN2A,  G.gallus
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
XP_425252.3
1494 aa
grin2a,  X.tropicalis
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
XP_002939231.2
1450 aa
grin2aa,  D.rerio
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a
XP_691754.3
1460 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

GRIN2A mutations cause epilepsy-aphasia spectrum disorders.
Carvill GL, et al. Nat Genet 45, 1073-6 (2013).
Short-term field stimulation mimics synaptic maturation of hippocampal synapses.
Bagley EE & Westbrook GL. J Physiol 590, 1641-54 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NMDAR2_C (pfam10565)
  N-methyl D-aspartate receptor 2B3 C-terminus.
PBPb (cd00134)
  Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic ...
NMDAR2_C (pfam10565)
  N-methyl D-aspartate receptor 2B3 C-terminus.
Periplasmic_Binding_Protein_Type_1 (cl10011)
  Type 1 periplasmic binding fold superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Grin2a includes H.sapiens GRIN2A and R.norvegicus Grin2a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 9 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Amphibia - amphibians (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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