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HomoloGene:1097. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   EREG,  H.sapiens
epiregulin
    NP_001423.1
169 aa
   EREG,  P.troglodytes
epiregulin
    XP_001155238.1
169 aa
   EREG,  M.mulatta
epiregulin
    XP_001102069.1
169 aa
   EREG,  C.lupus
epiregulin
    XP_005628350.1
157 aa
   EREG,  B.taurus
epiregulin
    XP_002688413.3
220 aa
   Ereg,  M.musculus
epiregulin
    NP_031976.1
162 aa
   Ereg,  R.norvegicus
epiregulin
    NP_067721.1
162 aa
   EREG,  G.gallus
epiregulin
    NP_001001203.1
153 aa
   ereg,  X.tropicalis
epiregulin
    NP_001039160.1
156 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Transformation of polarized epithelial cells by apical mistrafficking of epiregulin.
Singh B, et al. Proc Natl Acad Sci U S A 110, 8960-5 (2013).
Epiregulin as a marker for the initial steps of ovarian cancer development.
Amsterdam A, et al. Int J Oncol 39, 1165-72 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHA02887 (PHA02887)
  EGF-like protein; Provisional.
PHA03099 (PHA03099)
  epidermal growth factor-like protein (EGF-like protein); Provisional.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ereg includes H.sapiens EREG and R.norvegicus Ereg.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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