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HomoloGene:14174. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SLITRK1,  H.sapiens
SLIT and NTRK-like family, member 1
    NP_001268432.1
696 aa
   SLITRK1,  P.troglodytes
SLIT and NTRK-like family, member 1
    XP_001143864.1
696 aa
   SLITRK1,  M.mulatta
SLIT and NTRK-like family, member 1
    XP_001093240.1
696 aa
   SLITRK1,  C.lupus
SLIT and NTRK-like family, member 1
    XP_005634067.1
696 aa
   SLITRK1,  B.taurus
SLIT and NTRK-like family, member 1
    XP_003586770.1
696 aa
   Slitrk1,  M.musculus
SLIT and NTRK-like family, member 1
    NP_951020.1
696 aa
   Slitrk1,  R.norvegicus
SLIT and NTRK-like family, member 1
    NP_001100753.1
696 aa
   SLITRK1,  G.gallus
SLIT and NTRK-like family, member 1
    XP_416993.2
692 aa
   slitrk1,  X.tropicalis
SLIT and NTRK-like family, member 1
    NP_001096395.1
696 aa
   LOC558743,  D.rerio
SLIT and NTRK-like protein 1-like
    XP_005174686.1
689 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Tourette syndrome.



Publications
Articles associated with genes and sequences of this homology group.

The genetic basis of Gilles de la Tourette Syndrome.
Paschou P. Neurosci Biobehav Rev 37, 1026-39 (2013).
Association of SLITRK1 to Gilles de la Tourette Syndrome.
Miranda DM, et al. Am J Med Genet B Neuropsychiatr Genet 150B, 483-6 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR (smart00370)
  Leucine-rich repeats, outliers.
LRR_8 (pfam13855)
  Leucine rich repeat.
LRRCT (smart00082)
  Leucine rich repeat C-terminal domain.
LRR_8 (pfam13855)
  Leucine rich repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slitrk1 includes H.sapiens SLITRK1 and R.norvegicus Slitrk1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 6 species)
Aves - birds (3 transcripts, 2 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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