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HomoloGene:1229. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ALCAM,  H.sapiens
activated leukocyte cell adhesion molecule
    NP_001618.2
583 aa
   ALCAM,  P.troglodytes
activated leukocyte cell adhesion molecule
    XP_516634.2
583 aa
   ALCAM,  M.mulatta
activated leukocyte cell adhesion molecule
    XP_001099834.1
583 aa
   ALCAM,  C.lupus
activated leukocyte cell adhesion molecule
    XP_005639492.1
583 aa
   ALCAM,  B.taurus
activated leukocyte cell adhesion molecule
    NP_776663.1
583 aa
   Alcam,  M.musculus
activated leukocyte cell adhesion molecule
    NP_033785.1
583 aa
   Alcam,  R.norvegicus
activated leukocyte cell adhesion molecule
    NP_113941.1
583 aa
   ALCAM,  G.gallus
activated leukocyte cell adhesion molecule
    NP_990510.1
588 aa
   alcam,  X.tropicalis
activated leukocyte cell adhesion molecule
    NP_001072753.1
560 aa
   alcama,  D.rerio
activated leukocyte cell adhesion molecule a
    NP_571075.1
564 aa
   alcamb,  D.rerio
activated leukocyte cell adhesion molecule b
    NP_997799.3
562 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9.
Gilsanz A, et al. Cell Mol Life Sci 70, 475-93 (2013).
ALCAM (CD166) expression and serum levels in pancreatic cancer.
Tachezy M, et al. PLoS One 7, e39018 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ig_2 (pfam13895)
  Immunoglobulin domain.
IG_like (smart00410)
  Immunoglobulin like.
C2-set_2 (pfam08205)
  CD80-like C2-set immunoglobulin domain.
Ig (cl11960)
  Immunoglobulin domain.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Alcam includes H.sapiens ALCAM and R.norvegicus Alcam.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 12 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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