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HomoloGene:20167. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ADORA2B,  H.sapiens
adenosine A2b receptor
    NP_000667.1
332 aa
   ADORA2B,  P.troglodytes
adenosine A2b receptor
    XP_511779.2
332 aa
   ADORA2B,  M.mulatta
adenosine A2b receptor
    XP_001088484.2
394 aa
   ADORA2B,  C.lupus
adenosine A2b receptor
    NP_001002944.1
332 aa
   ADORA2B,  B.taurus
adenosine A2b receptor
    NP_001069393.1
332 aa
   Adora2b,  M.musculus
adenosine A2b receptor
    NP_031439.2
332 aa
   Adora2b,  R.norvegicus
adenosine A2B receptor
    NP_058857.1
332 aa
   ADORA2B,  G.gallus
adenosine A2b receptor
    NP_990418.1
340 aa
   adora2b,  X.tropicalis
adenosine A2b receptor
    XP_002938969.1
337 aa
   adora2b,  D.rerio
adenosine A2b receptor
    NP_001034902.1
351 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

A2B adenosine receptor blockade inhibits growth of prostate cancer cells.
Wei Q, et al. Purinergic Signal 9, 271-80 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Adora2b includes H.sapiens ADORA2B and R.norvegicus Adora2b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 8 species)
Actinopterygii - bony fishes (6 transcripts, 4 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

 

 

 

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