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HomoloGene:30948. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ADRB2,  H.sapiens
adrenoceptor beta 2, surface
    NP_000015.1
413 aa
   ADRB2,  P.troglodytes
adrenoceptor beta 2, surface
    NP_001182193.1
413 aa
   ADRB2,  M.mulatta
adrenoceptor beta 2, surface
    NP_001036239.1
415 aa
   ADRB2,  C.lupus
adrenoceptor beta 2, surface
    NP_001003234.1
415 aa
   ADRB2,  B.taurus
adrenergic, beta-2-, receptor, surface
    NP_776656.1
418 aa
   Adrb2,  M.musculus
adrenergic receptor, beta 2
    NP_031446.2
418 aa
   Adrb2,  R.norvegicus
adrenoceptor beta 2, surface
    NP_036624.2
418 aa
   ADRB2,  G.gallus
adrenergic, beta-2-, receptor, surface
    XP_004950644.1
397 aa
   adrb2,  X.tropicalis
adrenoceptor beta 2, surface
    NP_001116897.2
419 aa
   adrb2a,  D.rerio
adrenergic receptor, beta 2a
    NP_001096122.1
405 aa
   adrb2b,  D.rerio
adrenergic receptor, beta 2b
    NP_001082940.1
409 aa
   Octbeta2R,  D.melanogaster
Octbeta2R
    NP_001247076.1
536 aa
   GPRNNA2,  A.gambiae
GPRNNA2
    XP_003436280.1
526 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Beta-2-adrenoreceptor agonist, reduced response to.
Asthma, nocturnal, susceptibility to.
Obesity, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Reprogramming of G protein-coupled receptor recycling and signaling by a kinase switch.
Vistein R & Puthenveedu MA. Proc Natl Acad Sci U S A 110, 15289-94 (2013).
Conformational biosensors reveal GPCR signalling from endosomes.
Irannejad R, et al. Nature 495, 534-8 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Adrb2 includes H.sapiens ADRB2 and R.norvegicus Adrb2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (6 transcripts, 5 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

 

 

 

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