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HomoloGene:2145. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PYGM,  H.sapiens
phosphorylase, glycogen, muscle
    NP_005600.1
842 aa
   PYGM,  P.troglodytes
phosphorylase, glycogen, muscle
    XP_001165783.2
754 aa
   PYGM,  M.mulatta
phosphorylase, glycogen, muscle
    XP_001114805.1
842 aa
   PYGM,  C.lupus
phosphorylase, glycogen, muscle
    XP_853123.1
842 aa
   PYGM,  B.taurus
phosphorylase, glycogen, muscle
    NP_786980.1
842 aa
   Pygm,  M.musculus
muscle glycogen phosphorylase
    NP_035354.1
842 aa
   Pygm,  R.norvegicus
phosphorylase, glycogen, muscle
    NP_036770.1
842 aa
   LOC100491051,  X.tropicalis
glycogen phosphorylase, muscle form-like
    XP_002935410.2
843 aa
   pygma,  D.rerio
phosphorylase, glycogen (muscle) A
    NP_001018464.1
842 aa
   GlyP,  D.melanogaster
Glycogen phosphorylase
    NP_722762.1
844 aa
   AgaP_AGAP007939,  A.gambiae
AgaP_AGAP007939
    XP_317541.3
842 aa
   T22F3.3,  C.elegans
T22F3.3
    NP_504007.1
882 aa
   PHS2,  A.thaliana
PHS2
    NP_190281.1
841 aa
   Os01g0851700,  O.sativa
Os01g0851700
    NP_001044823.1
841 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
McArdle disease.



Publications
Articles associated with genes and sequences of this homology group.

McArdle disease: a novel mutation in Jewish families from the Caucasus region.
Haimi Cohen Y, et al. Mol Genet Metab 106, 379-81 (2012).
Glycogen Storage Disease Type V
Martín MA, et al. (1993).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Glycosyltransferase_GTB_type (cl10013)
  Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pygm includes H.sapiens PYGM and R.norvegicus Pygm.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (33 transcripts, 11 species)
Mammalia - mammals (16 transcripts, 14 species)
Amphibia - amphibians (6 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Hyperoartia - vertebrates (2 transcripts, 1 species)

Arthropoda
Insecta - insects (17 transcripts, 10 species)
Malacostraca - crustaceans (3 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (50 transcripts, 34 species)
Liliopsida - monocots (14 transcripts, 9 species)
Coniferopsida - conifers (8 transcripts, 3 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (4 transcripts, 2 species)

Dictyosteliida
Dictyostelium - cellular slime molds (2 transcripts, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

 

 

 

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