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HomoloGene:8040. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   RNASEL,  H.sapiens
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    NP_066956.1
741 aa
   RNASEL,  P.troglodytes
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    XP_524990.2
741 aa
   RNASEL,  M.mulatta
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    NP_001035898.1
729 aa
   RNASEL,  C.lupus
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    NP_001091018.1
724 aa
   RNASEL,  B.taurus
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    NP_001091634.1
723 aa
   Rnasel,  M.musculus
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
    NP_036012.1
735 aa
   Rnasel,  R.norvegicus
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    NP_872614.1
738 aa
   RNASEL,  G.gallus
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    NP_001026438.1
687 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Prostate cancer 1, 176807.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
RNase_Ire1_like (cl15368)
  RNase domain (also known as the kinase extension nuclease domain) of Ire1 and RNase L.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rnasel includes H.sapiens RNASEL and R.norvegicus Rnasel.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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