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HomoloGene:360. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   IL2RA,  H.sapiens
interleukin 2 receptor, alpha
    NP_000408.1
272 aa
   IL2RA,  P.troglodytes
interleukin 2 receptor, alpha
    NP_001030597.1
265 aa
   IL2RA,  M.mulatta
interleukin 2 receptor, alpha
    NP_001028089.1
272 aa
   IL2RA,  C.lupus
interleukin 2 receptor, alpha
    NP_001003211.1
268 aa
   IL2RA,  B.taurus
interleukin 2 receptor, alpha
    NP_776783.1
275 aa
   Il2ra,  M.musculus
interleukin 2 receptor, alpha chain
    NP_032393.3
268 aa
   Il2ra,  R.norvegicus
interleukin 2 receptor, alpha
    NP_037295.1
267 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Interleukin-2 receptor, alpha chain, deficiency of.
Diabetes mellitus, insulin-dependent, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

CD25 is a novel marker of hepatic bile canaliculus.
Lu ZH, et al. Int J Surg Pathol 20, 455-61 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CCP (cl00043)
  Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system.
CCP (cl00043)
  SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Il2ra includes H.sapiens IL2RA and R.norvegicus Il2ra.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)

 

 

 

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