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HomoloGene:4279. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   PURA,  H.sapiens
purine-rich element binding protein A
322 aa
   PURA,  P.troglodytes
purine-rich element binding protein A
322 aa
   PURA,  M.mulatta
transcriptional activator protein Pur-alpha-like
399 aa
   PURA,  C.lupus
purine-rich element binding protein A
322 aa
   PURA,  B.taurus
purine-rich element binding protein A
322 aa
   Pura,  M.musculus
purine rich element binding protein A
321 aa
   Pura,  R.norvegicus
purine rich element binding protein A
321 aa
   PURB,  G.gallus
purine-rich element binding protein B
275 aa
   pura,  X.tropicalis
purine-rich element binding protein A
282 aa
   pura,  D.rerio
purine-rich element binding protein A
287 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Role of Purα in the cellular response to ultraviolet-C radiation.
Kaminski R, et al. Cell Cycle 9, 4164-73 (2010).
Protective role of Puralpha to cisplatin.
Kaminski R, et al. Cancer Biol Ther 7, 1926-35 (2008).
Characterization of novel Pur alpha-binding proteins in mouse brain.
Zeng LH, et al. Neurochem Int 45, 753-8 (2004).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PUR (smart00712)
  DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pura includes H.sapiens PURA and R.norvegicus Pura.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Actinopterygii - bony fishes (17 transcripts, 8 species)
Mammalia - mammals (11 transcripts, 9 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)




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